Considering the new teachings that Islam brought with it, from the religious perspectives, the social divisions appeared in two periods of Maki (Muslim, infidels, idolaters) and Madani (infidels, idolaters, hypocrites, Muslims and believers). The Prophet's (PBUH) Hijra to Medina was the beginning of a new era in the history of Islam that led to the foundation of the newly established city-government of Medina. The issue of His succession was also a concern for this new political system. In fact, the issue of the Prophet’s succession after his death caused the division of the society. One of the events related to this issue was Ghadir Khumm. The role of the hypocrites, as one of the pillars of the new social structure which changed the meaning of Ghadir shouldn’t be ignored. This research attempts to investigate the role of the hypocrites in the issue of Ghadir Khumm, especially the issue of the succession of the Prophet (PBUH), through a descriptive-analytical method.