On the investigation of scientific life of the Imami scholars resided, gusted, or neighbored to Baytollah, their written and unwritten works in Mecca gain attentions. Writing books, reconstruction of Ka’bah, jurisprudential and narrative permission, comparison, correcting and reading the books of Imamyeh Figh and Hadith in Mecca and their scientific meetings which attracted the enthusiastic learners of Ahlul-Bayt’s sciences to Mecca show the substantial presence of scholars of Ahl ul-Bayt in this city. The most scientific and practical presence of the Imami scholars in Mecca were seen in the 11th century. Some of these scholars have had a high position in Mecca so that the books written by opponents in the past and present about Maki scholars have mentioned their names.