Different nations, schools and figures can be considered of influence in scientific flourishing of Islamic civilization. Kufic scientific school, considering its popular combination of A`arab and Persians and Imam Ali`s presence (a) and Imam Sadiq`s pupils caused a deep and comprehensive scientific movement there. This paper, using a library-based method and relying on authentic sources, has studied the part played by Kufic scientific movement in Islamic civilization during 36-448 of Hijrah. As is explained, such sciences as Quranic commentary, theology and jurisprudence have been established in Kufa. In addition, Kufic scholars have been of significant role in compiling and publishing other fields too. Kufic scientific heritage, then, arrived at other centers of Islamic sciences like those of Bghdad and Najaf.